Akti-1/2
Akti-1/2 (Akt Inhibitor VIII) is a highly selective Akt1/Akt2 inhibitor with IC50 of 58 nM/210 nM, respectively, about 36-fold selectivity for Akt1 over Akt3. Akti-1/2 induces apoptosis.
Trivial name | Akt Inhibitor VIII |
Catalog Number | S7776 |
Molecular Formula | C34H29N7O |
CAS# | 612847-09-3 |
Inchi | InChI=1S/C34H29N7O/c42-34-39-26-8-4-5-9-31(26)41(34)25-14-16-40(17-15-25)20-22-10-12-24(13-11-22)33-32(23-6-2-1-3-7-23)37-29-18-27-28(36-21-35-27)19-30(29)38-33/h1-13,18-19,21,25H,14-17,20H2,(H,35,36) (H,39,42) |
Inchi Key | BIWGYFZAEWGBAL-UHFFFAOYSA-N |
SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(N=C6C=C7C(=NC=N7)C=C6N5)C8=CC=CC=C8 |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/akti-1-2.html |
Additional Information | https://file.selleck.cn/downloads/struct/akti-1-chemical-structure-s7776.gif |