AZD8186
AZD8186 is a potent and selective inhibitor of PI3Kβ and PI3Kδ with IC50 of 4 nM and 12 nM, respectively. Phase 1.
| Trivial name | N/A |
| Catalog Number | S7694 |
| Molecular Formula | C24H25F2N3O4 |
| CAS# | 1627494-13-6 |
| Inchi | InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14-/m1/s1 |
| Inchi Key | LMJFJIDLEAWOQJ-CQSZACIVSA-N |
| SMILES | CC(C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/azd8186.html |
| Additional Information | https://file.selleck.cn/downloads/struct/azd8186-chemical-structure-s7694.gif |