D 4476
D 4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1δ, respectively. Also acts as an ALK5 inhibitor with IC50 of 500 nM.
| Trivial name | N/A |
| Catalog Number | S7642 |
| Molecular Formula | C23H18N4O3 |
| CAS# | 301836-43-1 |
| Inchi | InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27) |
| Inchi Key | DPDZHVCKYBCJHW-UHFFFAOYSA-N |
| SMILES | C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/d-4476.html |
| Additional Information | https://file.selleck.cn/downloads/struct/d-4476-chemcial-structure-s7642.gif |