Filgotinib (GLPG0634)
Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.
Trivial name | N/A |
Catalog Number | S7605 |
Molecular Formula | C21H23N5O3S |
CAS# | 1206161-97-8 |
Inchi | InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27) |
Inchi Key | RIJLVEAXPNLDTC-UHFFFAOYSA-N |
SMILES | C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5 |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/filgotinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/filgotinib-chemical-structure-s7605.gif |