Afuresertib (GSK2110183)
Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
| Trivial name | N/A |
| Catalog Number | S7521 |
| Molecular Formula | C18H17Cl2FN4OS |
| CAS# | 1047644-62-1 |
| Inchi | InChI=1S/C18H17Cl2FN4OS/c1-25-16(14(19)9-23-25)13-7-15(27-17(13)20)18(26)24-12(8-22)6-10-3-2-4-11(21)5-10/h2-5,7,9,12H,6,8,22H2,1H3,(H,24,26)/t12-/m0/s1 |
| Inchi Key | AFJRDFWMXUECEW-LBPRGKRZSA-N |
| SMILES | CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)NC(CC3=CC(=CC=C3)F)CN)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/afuresertib-gsk2110183.html |
| Additional Information | https://file.selleck.cn/downloads/struct/afuresertib-gsk2110183-chemical-structure-s7521.gif |