FRAX597
FRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.
Trivial name | N/A |
Catalog Number | S7271 |
Molecular Formula | C29H28ClN7OS |
CAS# | 1286739-19-2 |
Inchi | InChI=1S/C29H28ClN7OS/c1-3-37-27-20(14-24(28(37)38)23-9-4-19(15-25(23)30)26-17-31-18-39-26)16-32-29(34-27)33-21-5-7-22(8-6-21)36-12-10-35(2)11-13-36/h4-9,14-18H,3,10-13H2,1-2H3,(H,32,33,34) |
Inchi Key | DHUJCQOUWQMVCG-UHFFFAOYSA-N |
SMILES | CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)C4=CN=CS4)Cl)NC5=CC=C(C=C5)N6CCN(CC6)C |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/frax597.html |
Additional Information | https://file.selleck.cn/downloads/struct/frax597-chemical-structure-s7271.gif |