Siponimod (BAF312)
BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.
| Trivial name | N/A |
| Catalog Number | S7179 |
| Molecular Formula | C29H35F3N2O3 |
| CAS# | 1230487-00-9 |
| Inchi | InChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30,31)32/h9-14,22,25H,3-8,15-18H2,1-2H3,(H,35,36)/b33-19+ |
| Inchi Key | KIHYPELVXPAIDH-HNSNBQBZSA-N |
| SMILES | CCC1=C(C=CC(=C1)C(=NOCC2=CC(=C(C=C2)C3CCCCC3)C(F)(F)F)C)CN4CC(C4)C(=O)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/baf312-siponimod.html |
| Additional Information | https://file.selleck.cn/downloads/struct/baf312-siponimod-chemical-structure-s7179.gif |