SKI II
SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.
| Trivial name | SphK-I2 |
| Catalog Number | S7176 |
| Molecular Formula | C15H11ClN2OS |
| CAS# | 312636-16-1 |
| Inchi | InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18) |
| Inchi Key | ZFGXZJKLOFCECI-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ski-ii.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SKI-II-SphK-I2-chemical-structure-s7176.gif |