GW406108X

GW406108X (GW108X) is an inhibitor of Kif15 (Kinesin-12) with an IC50 of 0.82 μM in the ATPase assay. GW406108X inhibits recombinant ULK1 kinase activity with a pIC50 of 6.37 and blocks autophagy in cells, without affecting the upstream signalling kinases mTORC1 and AMPK.

Price Not Available 5mg GW406108X Supplier Page
Trivial name GW108X
Catalog Number S6953
Molecular Formula C20H11Cl2NO4
CAS# 1644443-92-4
Inchi #N/A
Inchi Key #N/A
SMILES OC1=C(Cl)C=C(C=C1Cl)/C=C/2C(=O)NC3=C2C=C(C=C3)C(=O)C4=CC=CO4
Size 5mg
Supplier Page http://www.selleckchem.com/products/gw406108x.html
Additional Information https://file.selleck.cn/downloads/struct/s6953-gw108x-chemical-structure.gif