MK-28
MK-28 is a potent and selective activator of PERK. MK-28 exhibits an IC50 ~3-fold higher than CCT020312 in rescuing mutant huntingtin protein (mHtt)-expressing striatal neurons from apoptosis. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice.
| Catalog Number | S6952 |
| Molecular Formula | C24H20N4O2 |
| CAS# | 864388-65-8 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/mk-28.html |
| Additional Information | https://file.selleck.cn/downloads/struct/S6952-MK-28-chemical-structure.png |