Pamufetinib (TAS-115)
Pamufetinib (TAS-115) is a highly potent c-Met and VEGFR dual inhibitor with IC50s of 30 nM and 32 nM for recombinant VEGFR2 and recombinant MET, respectively.
Trivial name | N/A |
Catalog Number | S6764 |
Molecular Formula | C27H23FN4O4S |
CAS# | 1190836-34-0 |
Inchi | InChI=1S/C27H23FN4O4S/c1-29-26(34)19-14-18-21(15-24(19)35-2)30-11-10-22(18)36-23-9-8-17(13-20(23)28)31-27(37)32-25(33)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H,29,34)(H2,31,32,33,37) |
Inchi Key | ORRNXRYWGDUDOG-UHFFFAOYSA-N |
SMILES | CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=C(C=C(C=C3)NC(=S)NC(=O)CC4=CC=CC=C4)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/tas-115.html |
Additional Information | https://file.selleck.cn/downloads/struct/s6764-pamufetinib-chemical-structure.gif |