AZD5069
AZD5069 is a novel antagonist of CXCR2, which is shown to inhibit binding of CXCL8 to CXCR2 with a pIC50 value of 8.8 and inhibit CXCL8 binding to CXCR1 with pIC50 values of 6.5.
| Trivial name | N/A |
| Catalog Number | S6645 |
| Molecular Formula | C18H22F2N4O5S2 |
| CAS# | 878385-84-3 |
| Inchi | InChI=1S/C18H22F2N4O5S2/c1-11(14(26)9-25)29-16-8-15(23-31(27,28)24-6-3-7-24)21-18(22-16)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,25-26H,3,6-7,9-10H2,1H3,(H,21,22,23)/t11-,14+/m1/s1 |
| Inchi Key | QZECRCLSIGFCIO-RISCZKNCSA-N |
| SMILES | CC(C(CO)O)OC1=NC(=NC(=C1)NS(=O)(=O)N2CCC2)SCC3=C(C(=CC=C3)F)F |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/azd-5069.html |
| Additional Information | https://file.selleck.cn/downloads/struct/azd-5069-chemical-structure-s6645.gif |