PMX-53
PMX-53 is a potent CD88 (C5aR) antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).
| Trivial name | N/A |
| Catalog Number | S6239 |
| Molecular Formula | C47H65N11O7 |
| CAS# | 219639-75-5 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5CCCCC5)NC(=O)C6CCCN6C2=O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/pmx-53.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6239-pmx-53-chemical-structure.gif |