YUM70
YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78) inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism.
| Trivial name | N/A |
| Catalog Number | S6193 |
| Molecular Formula | C21H19ClN2O4 |
| CAS# | 423145-35-1 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CCCC(=O)NC(C1=CC2=C(OCO2)C=C1)C3=CC(=C4C=CC=NC4=C3O)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/yum70.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6193-yum70-chemical-structure.gif |