ICCB-19 hydrochloride
ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy.
| Trivial name | N/A |
| Catalog Number | S6078 |
| Molecular Formula | C12H22ClN3OS |
| CAS# | 1803605-68-6 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | Cl.O=C(CSC1=NCCN1)NC2CCCCCC2 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/iccb-19-hydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6078-iccb-19-hydrochloride-chemical-structure.gif |