QNZ (EVP4593)
QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively.
| Trivial name | N/A |
| Catalog Number | S4902 |
| Molecular Formula | C22H20N4O |
| CAS# | 545380-34-5 |
| Inchi | InChI=1S/C22H20N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11,14-15H,12-13,23H2,(H,24,25,26) |
| Inchi Key | IBAKVEUZKHOWNG-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/qnz-evp4593.html |
| Additional Information | https://file.selleck.cn/downloads/struct/QNZ-chemical-structure-s4902.gif |