Nilotinib hydrochloride monohydrate

Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.

Trivial name Tasigna, AMN-107 hydrochloride monohydrate
Catalog Number S4895
Molecular Formula C28H25ClF3N7O2
CAS# 923288-90-8
Inchi #N/A
Inchi Key #N/A
SMILES O.Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)NC(=O)C3=CC(=C(C)C=C3)NC4=NC=CC(=N4)C5=CN=CC=C5)C(F)(F)F
Size 25mg
Supplier Page http://www.selleckchem.com/products/nilotinib-hydrochloride-monohydrate.html
Additional Information https://file.selleck.cn/downloads/struct/s4895-nilotinib-hydrochloride-monohydrate-chemical-structure.gif