Nilotinib hydrochloride monohydrate
Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
Trivial name | Tasigna, AMN-107 hydrochloride monohydrate |
Catalog Number | S4895 |
Molecular Formula | C28H25ClF3N7O2 |
CAS# | 923288-90-8 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | O.Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)NC(=O)C3=CC(=C(C)C=C3)NC4=NC=CC(=N4)C5=CN=CC=C5)C(F)(F)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/nilotinib-hydrochloride-monohydrate.html |
Additional Information | https://file.selleck.cn/downloads/struct/s4895-nilotinib-hydrochloride-monohydrate-chemical-structure.gif |