Teriflunomide
Teriflunomide (A77 1726, HMR-1726) is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.
| Trivial name | A77 1726, HMR-1726 |
| Catalog Number | S4169 |
| Molecular Formula | C12H9F3N2O2 |
| CAS# | 163451-81-8 |
| Inchi | InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7- |
| Inchi Key | UTNUDOFZCWSZMS-YFHOEESVSA-N |
| SMILES | CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/teriflunomide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/teriflunomide-chemical-structure-s4169.gif |