Harmine hydrochloride

Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.

Price Not Available 10mM/1mL Harmine hydrochloride Supplier Page

Trivial name	Telepathine hydrochloride
Catalog Number	S3817
Molecular Formula	C13H12N2O.HCl
CAS#	343-27-1
Inchi	InChI=1S/C13H12N2O.ClH/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13;/h3-7,15H,1-2H3;1H
Inchi Key	VNPLYCKZIUTKJM-UHFFFAOYSA-N
SMILES	CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC.Cl
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/harmine-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/harmine-hydrochloride-chemical-structure-s3817.gif