Zandelisib
Zandelisib(ME-401; PWT-143) is an orally bioavailable inhibitor of the phosphatidylinositide 3-kinase (PI3K). It selectively inhibits the delta isoform of PI3K (p110δ) and prevents the activation of the PI3K/AKT signaling pathway with an IC50 of 3.5 nM. It functions as an antineoplastic agent.
| Trivial name | ME-401; PWT-143 |
| Catalog Number | S3575 |
| Molecular Formula | C16H14BrNO5S |
| CAS# | 1401436-95-0 |
| Inchi | InChI=1S/C16H14BrNO5S/c17-10-3-8(4-11(19)15(10)22)1-2-14(24)18-7-9-5-12(20)16(23)13(21)6-9/h1-6,19-23H,7H2,(H,18,24)/b2-1+ |
| Inchi Key | NIPUPOUEGOSAAO-OWOJBTEDSA-N |
| SMILES | C1=C(C=C(C(=C1O)O)O)CNC(=S)C=CC2=CC(=C(C(=C2)Br)O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/zandelisib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/S3575-Zandelisib-chemical-structure.png |