IDH-305
IDH-305 (Compound 13) is an orally available, mutant-selective and brain-penetrant inhibitor of isocitrate dehydrogenase 1 (IDH1) that targets IDH1(R132) mutation with IC50 of 27 nM, 28 nM and 6.14 μM for IDH1R132H, IDH1R132C and IDH1WT, respectively.
| Trivial name | N/A |
| Catalog Number | S3574 |
| Molecular Formula | C23H22F4N6O2 |
| CAS# | 1628805-46-8 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/idh-305.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s3574-idh-305-chemical-structure.gif |