Daporinad (FK866)
Daporinad (FK866) effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase; Nampt) with IC50 of 0.09 nM in a cell-free assay. Daporinad (FK866, APO866) triggers autophagy. Phase 1/2.
| Trivial name | APO866 |
| Catalog Number | S2799 |
| Molecular Formula | C24H29N3O2 |
| CAS# | 658084-64-1 |
| Inchi | InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+ |
| Inchi Key | KPBNHDGDUADAGP-VAWYXSNFSA-N |
| SMILES | C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/apo866-fk866.html |
| Additional Information | https://file.selleck.cn/downloads/struct/APO866-chemical-structure-s2799.gif |