AV-412 free base
AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.51, 0.79, 2.30, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.
| Trivial name | MP-412 free base |
| Catalog Number | S2733 |
| Molecular Formula | C27H28ClFN6O |
| CAS# | 451492-95-8 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CN1CCN(CC1)C(C)(C)C#CC2=CC3=C(C=C2NC(=O)C=C)C(=NC=N3)NC4=CC(=C(F)C=C4)Cl |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/av-412-free-base.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2733-av-412-free-base-chemical-structure.gif |