AZ 3146
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
| Trivial name | N/A |
| Catalog Number | S2731 |
| Molecular Formula | C24H32N6O3 |
| CAS# | 1124329-14-1 |
| Inchi | InChI=1S/C24H32N6O3/c1-28-12-10-17(11-13-28)33-18-8-9-19(21(14-18)32-3)26-23-25-15-20-22(27-23)30(24(31)29(20)2)16-6-4-5-7-16/h8-9,14-17H,4-7,10-13H2,1-3H3,(H,25,26,27) |
| Inchi Key | YUKWVHPTFRQHMF-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/az-3146.html |
| Additional Information | https://file.selleck.cn/downloads/struct/az-3146-chemical-structure-s2731.gif |