Neflamapimod (VX-745)

Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.

Price Not Available 10mM/1mL Neflamapimod (VX-745) Supplier Page
Trivial name N/A
Catalog Number S1458
Molecular Formula C19H9Cl2F2N3OS
CAS# 209410-46-8
Inchi InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H
Inchi Key VEPKQEUBKLEPRA-UHFFFAOYSA-N
SMILES C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/VX-745.html
Additional Information https://file.selleck.cn/downloads/struct/VX-745-chemical-structure-S1458.gif