BMS-536924
BMS-536924 (CS-0117) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
| Trivial name | CS-0117 |
| Catalog Number | S1012 |
| Molecular Formula | C25H26ClN5O3 |
| CAS# | 468740-43-4 |
| Inchi | InChI=1S/C25H26ClN5O3/c1-15-11-18(31-7-9-34-10-8-31)13-20-23(15)30-24(29-20)22-19(5-6-27-25(22)33)28-14-21(32)16-3-2-4-17(26)12-16/h2-6,11-13,21,32H,7-10,14H2,1H3,(H,29,30)(H2,27,28,33)/t21-/m1/s1 |
| Inchi Key | ZWVZORIKUNOTCS-OAQYLSRUSA-N |
| SMILES | CC1=CC(=CC2=C1N=C(N2)C3=C(C=CNC3=O)NCC(C4=CC(=CC=C4)Cl)O)N5CCOCC5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/BMS-536924.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BMS-536924-chemical-structure-S1012.gif |