SKI-V
SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.
| Trivial name | N/A |
| Catalog Number | S0817 |
| Molecular Formula | C15H10O4 |
| CAS# | 24418-86-8 |
| SMILES | C1=CC=C2C(=C1)C(=O)C(=CC3=CC(=C(C=C3)O)O)O2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ski-v.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0817-ski-v-chemical-structure.gif |