NL-1
The mitochondrial mitoNEET ligand NL-1 is a mitoNEET inhibitor, which induces a concentration-dependent decrease in cell viability with an IC50 of 47.35 μM and 56.26 μM in REH and REH/Ara-C cells respectively. The docking studies using liver mitochondrial suspensions show the IC50 of NL-1 binding for [3H]-rosiglitazone is 0.9 μM and the Ki for NL-1 site 1 and site 2 was 4.78 and 2.77, respectively.
| Trivial name | N/A |
| Catalog Number | S0767 |
| Molecular Formula | C18H25NO3S |
| CAS# | 188532-26-5 |
| SMILES | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC2C(=O)NC(=O)S2 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/nl-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0767-nl-1-chemical-structure.gif |