MMAF
MMAF (Monomethylauristatin F) is a synthetic antineoplastic agent and a potent inhibitor of tubulin polymerization. MMAF (Monomethylauristatin F) is applied as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin, ABT-414 and SGN-CD19A.
| Trivial name | Monomethylauristatin F |
| Catalog Number | S0328 |
| Molecular Formula | C39H65N5O8 |
| CAS# | 745017-94-1 |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/mmaf.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0328-mmaf-chemical-structure.gif |