IAXO-102
IAXO-102 is an antagonist of TLR4 targeting both MD-2 and CD14 co-receptors. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and downregulates the expression of TLR4 dependent proinflammatory proteins. IAXO-102 inhibits experimental abdominal aortic aneurysm (AAA) development.
Trivial name | N/A |
Catalog Number | S0002 |
Molecular Formula | C35H71NO5 |
CAS# | 1115270-63-7 |
SMILES | CCCCCCCCCCCCCCOC1C(C(OC(C1OCCCCCCCCCCCCCC)OC)CN)O |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/iaxo-102.html |
Additional Information | https://file.selleck.cn/downloads/struct/s0002-iaxo-102-chemical-structure.gif |