Crataegi Fructus Extract is extracted from the fruits of Crataegi fructus (hawthorn). Crataegi fructus is dry ripe fruit of Crataegus pinnatifida Bge.var. major N. E. Br. or Crataegus pinnatifida Bge.. The extracts and compounds from fructus crataegi show a variety of pharmacological activities, such as a protective effect on patients with heart failure, as well as an increased force of myocardial contraction, improved coronary circulation, antioxidant effects and antimicrobial activities.