RGB-286638 free base
RGB-286638 free base is a Cyclin-dependent kinase (CDK) inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
Catalog Number | E2821 |
CAS# | 784210-88-4 |
Inchi | #N/A |
Inchi Key | #N/A |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/rgb-286638-free-base.html |
Additional Information | https://file.selleck.cn/downloads/struct/e2821-rgb-286638-free-base-chemical-structure.gif |