Kira8
Kira8 (Ire-1 inhibitor, AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
| Trivial name | Ire-1 inhibitor,AMG-18 |
| Catalog Number | E2652 |
| Molecular Formula | C31H29ClN6O3S |
| CAS# | 1630086-20-2 |
| SMILES | CC1=C(OC2=C(C=CC=N2)C3=NC(=NC=C3)NC4CCCNC4)C5=C(C=C1)C(=CC=C5)N[S;v6](=O)(=O)C6=C(Cl)C=CC=C6 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/kira8.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e2652-kira8-chemical-structure.gif |