Nesuparib
Nesuparib (JPI-547, NOV140201) is a potential inhibitor of both PARP and tankyrases, with IC50 of 0.005 μM, 0.001 μM, 0.002 μM, and ND for TNKS1, TNKS2, PARP1, and PARP2, respectively. Nesuparib exhibits anti-tumor activity in BRCA-deficient xenograft models.
| Trivial name | JPI-547, NOV140201 |
| Catalog Number | E1425 |
| Molecular Formula | C23H24N6O |
| CAS# | 2055357-64-5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/nesuparib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e1425-nesuparib-chemical-structure.png |