SKLB-197
SKLB-197 exerts selectively inhibition against ataxia telangiectasia mutated and Rad3-related (ATR) kinase with IC50 of 0.013 μM, also displays potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.
Catalog Number | E1136 |
Molecular Formula | C25H24N6O |
CAS# | 2713577-16-1 |
SMILES | CC1COCCN1C2=NC(=NC3=C2C=C(C=C3)C4=CC=N[N]4C)C5=C6C=C[NH]C6=CC=C5 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/sklb-197.html |
Additional Information | https://file.selleck.cn/downloads/struct/e1136-sklb-197-chemical-structure.gif |