Senicapoc (ICA-17043)
Senicapoc (ICA-17043) is a Gardos channel(Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM and produces dose-dependent increases in hemoglobin and decreases in markers of hemolysis. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.
| Catalog Number | E0501 |
| Molecular Formula | C20H15F2NO |
| CAS# | 289656-45-7 |
| SMILES | NC(=O)C(C1=CC=CC=C1)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/senicapoc-ica-17043.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e0501-senicapoc-ica-17043-chemical-structure.gif |