Parsaclisib (INCB050465)
Parsaclisib (INCB050465, INCB-50465, IBI376) is a potent and highly selective PI3Kδ(PI3K delta) inhibitor with an IC50 of 1 nM at 1 mM ATP in biochemical assay and approximately 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ; and 57 other kinases.
Trivial name | INCB-50465, IBI376 |
Catalog Number | E0121 |
Molecular Formula | C20H22ClFN6O2 |
CAS# | 1426698-88-5 |
SMILES | CCOC1=C(C2CNC(=O)C2)C(=C(Cl)C=C1C(C)[N]3N=C(C)C4=C(N)N=CN=C34)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/parsaclisib-incb050465.html |
Additional Information | https://file.selleck.cn/downloads/struct/e0121-parsaclisib-chemical-structure.gif |