2-BP (2-Bromohexadecanoic acid)
2-BP (2-Bromohexadecanoic acid) is a nonmetabolisable analogue of palmitate and acts as a palmitoylation inhibitor, which inhibits multiple palmitoyl-acyl transferase (PAT) activity towards MyrGCK(NBD) and FarnCNRas(NBD) with identical IC50s of approx. 4 µM. 2-Bromohexadecanoic acid can directly and irreversibly inhibit the palmitoyltransferase activity of all DHHC (Asp-His-His-Cys) proteins.
Trivial name | 2-bromopalmitate |
Catalog Number | E0120 |
Molecular Formula | C27H29ClN2O4S2 |
CAS# | 18263-25-7 |
SMILES | CCCOC1=C(CN(CCC2=CC=C(C=C2)[S](=O)(=O)NCC#C)C(=O)CC3=CSC=C3)C=C(Cl)C=C1 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/2-bromohexadecanoic-acid.html |
Additional Information | https://file.selleck.cn/downloads/struct/e0120-2-bromohexadecanoic-acid-chemical-structure.gif |