(R,R)-GSK321| ChemScene
(R,R)-GSK321 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. (R,R)-GSK321 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity.IC50 & Target:IC50: 120 nM (WT IDH1)In Vitro:(R,R)-GSK321 (0.1~3 μM; 5 hours; A-498 cells) dose dependent decreases in reductive glutaminolysis.
| Trivial name | (R,R)-GSK321 |
| Catalog Number | CS-0101883 |
| Molecular Formula | 501.55 |
| CAS# | 1816272-19-1 |
| Purity | >98% |
| Condensed Formula | C28H28FN5O3 |
| Size | 5mg |
| Supplier Page | www.chemscene.com/1816272-19-1.html |