TCID| ChemScene

TCID (4,5,6,7-Tetrachloroindan-1,3-dione) is a potent and selective neuronal ubiquitin C-terminal hydrolase (UCH-L3) inhibitor with an IC50 of 0.6 μM. TCID diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons[2].IC50 & Target: IC50: 0.6 μM (UCH-L3) and 75 μM (UCH-L1)In Vitro: TCID (4,5,6,7-Tetrachloroindan-1,3-dione; compound 11) inhibits UCH-L1 with an IC50 of 75 μM.
TCID (10 μM; 1, 2 hours) diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons[2].

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Trivial name TCID
Catalog Number CS-0011637
Alternative Name(s) 4,5,6,7-Tetrachloroindan-1,3-dione
Molecular Formula 283.92
CAS# 30675-13-9
Purity >98%
Condensed Formula C9H2Cl4O2
Size 1mg
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