Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton.IC50 & Target: NematodesIn Vitro: Tioxazafen has direct nematicidal activity against RKN (M. incognita) and SCN (H. glycines) and is as effective as nematicidal active ingredients of commercial standards in causing nematode mortality. Tioxazafen exhibits excellent activity against soybean cyst, root knot, and reniform nematodes in soy; lesion, root knot, and needle nematodes in corn; as well as reniform and root knot nematodes in cotton.