Reversine
A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66 μM) and an aurora kinase inhibitor (IC50’s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound.
| Catalog Number | ABS-059 |
| Alternative Name(s) | 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine |
| CAS# | 656820-32-5 |
| Inchi | InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27) |
| Inchi Key | ZFLJHSQHILSNCM-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/reversine-item-1523.html |