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A relatively non-toxic Inhibitor of histone deacetylase (HDAC). Facilitates transcriptional activation (TGF-β/Smad4) in both stable and transient receptor assays in a concentration-dependent manner. At ~2 µg/mL (6-8 µM) concentrations, results in a greater than 100-fold increase in histone acetylation in PANC-1 cells.

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Catalog Number ABH-023
Alternative Name(s) N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide
CAS# 287383-59-9
Inchi InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9,24H,1-3,10-11H2,(H,19,21)
Inchi Key JTDYUFSDZATMKU-UHFFFAOYSA-N
SMILES C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO
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