SBHA
SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 μM) and HDAC3 (IC50 = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines.
Catalog Number | ABH-022 |
Alternative Name(s) | Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N'-dihydroxyoctanediamide |
CAS# | 38937-66-5 |
Inchi | InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12) |
Inchi Key | IDQPVOFTURLJPT-UHFFFAOYSA-N |
SMILES | C(CCCC(=O)NO)CCC(=O)NO |
Size | Inquiry |
Supplier Page | https://www.agingclocks.com/sbha-item-1437.html |