Sclerotiorin
An antibiotic Isolated from fungus Penicillium sp. Cholesteryl ester transfer protein (CETP) activity inhibitor (IC50 = 19.4 µM). Weak antagonist of human endothelin receptor A (ETA) and B (ETB). A potent aldose reductase inhibitor and a potent reversible, non-competitive soybean lipoxygenase-1 (LOX-1) inhibitor. Also acts as an antioxidant and a free radical scavenger.
Catalog Number | ABA-043 |
Alternative Name(s) | (S-(R*,R*-(E,E)))-Sclerotiorin |
CAS# | 549-23-5 |
Inchi | InChI=1S/C21H23ClO5/c1-6-12(2)9-13(3)7-8-15-10-16-17(11-26-15)19(24)21(5,27-14(4)23)20(25)18(16)22/h7-12H,6H2,1-5H3/b8-7+,13-9+/t12-,21+/m0/s1 |
Inchi Key | SWJLTKXURNHVHE-UPWXJBBJSA-N |
SMILES | CCC(C)C=C(C)C=CC1=CC2=C(C(=O)C(C(=O)C2=CO1)(C)OC(=O)C)Cl |
Size | Inquiry |
Supplier Page | https://www.agingclocks.com/sclerotiorin-item-1410.html |