UNC5293
UNC5293 is a potent, orally available and highly MERTK-selective inhibitor with Ki of 190 pM. UNC5293 inhibits MERTK ( IC 50 =0.9 nM) and is more selective over Axl, Tyro3 and Flt3. UNC5293 exhibits excellent mouse PK properties and is used for bone marrow leukemia research [1].
| Catalog Number | T9134 |
| Molecular Formula | C30H42N6O2 |
| CAS# | 2226789-82-6 |
| SMILES | CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)C1CCN(CC1)C(=O)c1cc(C)nc(C)c1 |
| Size | 1 mg |
| Supplier Page | https://www.targetmol.com/compound/unc5293 |
| Additional Information | https://www.targetmol.com/datasheet/T9134 |
