BSJ-4-116
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
| Catalog Number | T9117 |
| Research Area | Cell Cycle/Checkpoint|||PROTAC |
| Molecular Formula | C40H49ClN8O8S |
| CAS# | 2519823-34-6 |
| Purity | 99.09% |
| SMILES | O=C(NCCCCCCCN1C[C@H](NC2=NC=C(Cl)C(NC3=CC=CC=C3S(=O)(C(C)C)=O)=N2)CCC1)COC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O |
| Size | 100 mg |
| Supplier Page | https://www.targetmol.com/compound/BSJ-4-116 |
| Additional Information | https://www.targetmol.com/datasheet/T9117 |