β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides , acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC 50 s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells [1] .