YX-2-107

YX-2-107 is a selective and potent CDK6-degrading PROTAC with an IC50 value of 4.4 nM.YX-2-107 inhibits RB phosphorylation and FOXM1 expression in vitro, and inhibits the development of Ph+ ALL in rats.YX-2-107 can be used for the prophylaxis and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). YX-2-107 can be used for the prevention and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

Price Not Available 50 mg YX-2-107 Supplier Page

Catalog Number	T74710
Research Area	Cell Cycle/Checkpoint
Molecular Formula	C45H51N11O9
CAS#	2417408-46-7
SMILES	O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCC(=O)NCCCCNCC(=O)N4CCN(C5=CN=C(C=C5)NC=6N=CC7=C(N6)N(C(=O)C(C(=O)C)=C7C)C8CCCC8)CC4)C3C2=O)CC1
Size	50 mg
Supplier Page	https://www.targetmol.com/compound/yx-2-107
Additional Information	https://www.targetmol.com/datasheet/T74710