USP8-IN-3
USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D. USP8-IN-3 inhibited the proliferation of GH3 and H1957 cells with GI50 values of 37.03 μM and 6.01 μM, respectively. USP8-IN-3 is a potential compound for the treatment of cancer and viral infections.
| Catalog Number | T67873 |
| Research Area | Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination |
| Molecular Formula | C18H18F3N5O2S |
| CAS# | 2477651-10-6 |
| Purity | 99.18% |
| SMILES | O=[N+]([O-])C1=CC=C(NC(NC2CCN(CC2)C3=CC=CC(C(F)(F)F)=N3)=S)C=C1 |
| Size | 50 mg |
| Supplier Page | https://www.targetmol.com/compound/usp8-in-3 |
| Additional Information | https://www.targetmol.com/datasheet/T67873 |
